We stand at the frontiers of chemistry and biology, developing small molecules as chemical tools to understand and modulate complex biological systems. We utilize synthetic chemistry, biochemistry, and state-of-the art mass spectrometry to elucidate the structure, dynamics, and reactivity of poorly characterized, previously "undruggable" members of the proteome with pathological implications (e.g. cancer, diabetes, infectious diseases).
More Details
Congrats Dany, Nan, Brittney, Daniel (and all authors) on publishing this exciting article in JACS!
November 5, 2025
Check out this awesome article where they discuss the conjugation of antibodies with a small ketoboronate-based, lysine-reactive, covalent-reversible uptake tag (KB) for plasma membrane internalization and extracellular proteins, directing them to lysosomal degradation via receptor-mediated endocytosis now online in Journal of American Chemical Society!
Welcome Hengbo (Bob) and Jingsheng (Ivy) to the Adibekian Lab!
September 29, 2025
​
We would like to warmly welcome Bob and Ivy, new Postdoctoral Research Associates who got their PhD in Medicinal Chemistry from the Shanghai Institute of Materia Medica to the Adibekian Lab! We look forward to work with you guys and achieve great milestones in Chemistry!
Congrats Nan (and all authors) on publishing this impressive review article in Angewandte Chemie!
August 22, 2025
Check out this interesting review article where they discuss modern synthetic methods for the preparation of aziridine-containing small molecules as activity based probes for glycosidases, drug development, proteomics, and lipidomics now online in Angewandte Chemie!
Latest Lab News
Learn more about our lab by clicking on the icons below.
Lab Culture
We strive to make our lab a family by cultivating a fun yet hardworking lab environment. We regularly partake in lab events, such lab dinners and team-building activities.